The Madina to Osu trotro transit follows the Adenta highway. It leads out from the Madina trotro station along the road through the Legon school to Shiashie. From there it goes through the Liberation road all the way to the Airport and 37. Ot then turns left towards Elwak and goes through the Cantonments post office, Accra Land Valuation and the Ghana International school route before it continues to the Osu Presby school as the last stop.